Dilution and dosing of peptides in simple terms. Dilution and dosing of peptides in simple terms What are they used for and side effects
GHRP-6 and Hexarelin (from the English Growth Hormone Releasing Peptide - 2 - a peptide that releases growth hormone and from the English Hexarelin)- stimulants of growth hormone secretion. Hexarelin is a structural analogue of GHRP-6, has the same effects, is used in the same dosages, so they are often considered synonyms. These substances were developed to treat growth hormone deficiency.
GHRP-6 is in many ways similar to GHRP-2, the main difference is that the second is approximately 1.5 times more powerful growth hormone booster, can increase appetite somewhat more strongly (although comparative studies have not been conducted), but at the same time increases the concentration of prolactin and cortisol. These peptides can be used together to achieve a synergistic effect. In studies, the maximum concentrations of growth hormone in the blood were observed with the combined administration of GHRP-6 and GHRP-2.
Recently, erroneous opinions have been spreading about the effect of these ghrelin agonists on appetite, especially when doctors from the Iron World published an article (Peptides part 1, author Dmitry Ustimenko), where they wrote: Ghrelin is an appetite hormone. Stimulated by GHRP-6 and GHRP-2. Ghrelin release is influenced more by GHRP-6 than by GHRP-2. This is a gross misconception, since they in no way stimulate the production of ghrelin, but are mimetics to its receptors. At the same time, GHRP-2 has greater affinity, and in addition, the effect of cortisol is additionally superimposed, which also increases appetite. As a result, illiterate readers of the magazine, deprived of the ability to critically think, began to actively replicate false information. The article contains many other errors and false statements regarding effects and pharmacodynamics.
Hexarelin and GHRP-6 can be administered into the body in various ways: subcutaneously, orally, sublingually, buccally, but most often intramuscularly. The molecules of this substance are so small that they are able to penetrate the blood vessels of the mouth and stomach before being destroyed by digestive enzymes.
Application in bodybuilding
Despite the fact that this is a new drug, Hexarelin has already become a popular choice for athletes as a means to increase endurance and increase muscle definition. GHRP-6 is available in several brands.
Action
The main effect of GHRP-6 is to stimulate the secretion of growth hormone, so most of the effects are similar to those of growth hormone.
The main effects of GHRP-6 are listed below:
- Muscle growth;
- Fat burning;
- Increased relief;
- Increased appetite;
- Strengthening immunity;
- Strengthening bones;
- Protects the liver;
Research data
In studies when Hexarelin was administered subcutaneously, growth hormone concentrations increased significantly within thirty minutes after administration. Over the next four hours after the injection, the concentration of growth hormone gradually decreases to the initial level.
Dosages and regimen
Tests have shown that the optimal single dosage of GHRP-6 is 1 mcg per 1 kg of body weight. When the dosage is reduced, a weaker rise in growth hormone is observed, but exceeding the specified dosage does not lead to an increase in the secretion of growth hormone. For example, when increasing the dosage from 100 to 200 mcg, the increase in growth hormone concentration will differ by only 25%, so 100 mcg is considered the optimal dosage for bodybuilding. The drug is administered three times a day - after training, 15 minutes before meals and before bedtime.
It was also determined that the body gradually adapts to the action of GHRP-6, and the effectiveness of the drug decreases accordingly. In the people studied, tolerance (desensitization) occurred after 4-16 weeks of use. For this reason, if you do not want to waste your financial resources, the duration of the course should not exceed 4-8 weeks, after which you need to take a break for 1-2 weeks.
The problem of desensitisation is also solved by the combination with CJC-1295; currently this “combination is recognized as the gold standard.”
Combination
The effectiveness of a GHRP-6 cycle can be significantly increased if you combine it with other growth hormone stimulants.
- CJC-1295 or GRF(1-29) - the best choice for combination. They enhance the effect of GHRP-6 several times. This combination is currently recognized as the gold standard in bodybuilding. Combined courses are described in the links provided;
- GHRP-2 - will increase the effectiveness of the course by more than 2 times;
- Insulin - will increase the effectiveness of the course by 30-40%;
- Arginine - will increase efficiency by 10-20%;
- Glutamine;
- GABA.
Side effects
During the studies, no serious side effects of GHRP-6 were recorded; on the contrary, the drug increased the body’s protective properties. GHRP-6 is prescribed even in childhood. At higher dosages (600 mcg/day and above), it can cause an increase in the concentration of prolactin and cortisol, but to a much lesser extent than GHRP-2. A burning sensation occurs at the injection sites, which goes away after 5-10 minutes.
GHRP-6 course for strength and muscle mass
Here you will need to give 3 injections per day of 100 micrograms of the substance. Inexpensive and effective course for 2 months. GHRP-6 should be administered no earlier than 40-60 minutes after a meal; after GHRP-6, do not eat carbohydrates and fats; ideally, it is better not to eat anything. After 40 minutes, the release of growth hormone begins to decline and then you can eat. Proteins prolong the release, especially glutamine, arginine, D-aspartic acid.
Result:
- Increase in strength indicators;
- Muscle growth;
- Fat burning;
- Increased relief;
- Anti-aging effect (improving the properties of skin and hair);
- Strengthening immunity;
- Strengthening bones;
- Protects the liver;
- Anti-inflammatory effect.
Basic combined course CJC-1295 + GHRP-6
It has been well proven and well established that the simultaneous administration of GHRH (eg, CJC-1295) and GHRP (eg, GHRP-6 or GHRP-2) leads to a synergistic effect. These peptides have a potentiating effect on each other. In other words, with the introduction of one CJC-1295 we will get a stimulating effect of 2 points. When introducing GHRP-6 alone, we get an effect of 4 points. When both substances are administered simultaneously, we will get an effect not of 6 points (additive effect 2+4=6), as one might expect, but of 10 points - more than the sum of each separately (potentiating effect 2+4=10). This way we not only get a greater anabolic response, but we can also save money.
Although the natural growth hormone surge is maintained when CJC-1295 is administered, it does not cause an increase in these peaks, only increasing the basal level of growth hormone, thus creating a pattern of concentrations according to female type with less anabolic response. Moreover, GHRH are only effective when somatostatin levels are low. Therefore, combining CJC-1295 and GHRP-6 or GHRP-2 allows you to maintain the natural curve, and adjust the time and height of concentration peaks.
Optimal combined course:
GHRP-6 or GHRP-2 100 mcg three times a day.
CJC-1295 1000 mcg twice a week.
Course duration is 8-12 weeks.
Its effectiveness is equal to a growth hormone cycle of 15 units/day, while the cost is several times lower.
CJC-1295 course without DAC
Optimal dosage of CJC-1295 without DAC: 1 mcg/kg up to three times daily (by subcutaneous injection) (2 mg ampoule = 2000 mcg). Thus, with a weight of 90 kg, the relevant dosage would be 90 mcg, and one bottle will last for 8-22 days (depending on the frequency of use).
It is also advisable to combine this peptide with GHRP-6 or GHRP-2. For example, the standard protocol looks like this: one injection contains 100 μg of GHRP-6 + 100 μg of modified GRF (1-29). Can be dissolved in one syringe. The solution is diluted 2-3 times a day, with a difference of at least 3 hours. Best time for injection: after training, 15 minutes before meals and before bed!
Dosages and regimen (3 times a day):
100mcg CJC-1295 along with 200mcg GHRP-6 in the morning 25 minutes before meals
100mcg CJC-1295 along with 200mcg GHRP-6 6 hours later, ideally immediately after training
100mcg CJC-1295 along with 200mcg GHRP-6 immediately before bed
Main effects:
- Increase in strength indicators;
- Muscle growth;
- Fat burning.
- Minor effects:
- Strengthening ligaments, joints, bones;
- Strengthening immunity;
- Rejuvenating effect;
- Improving the properties of skin and hair;
- Increased relief;
- Protects the liver;
- Anti-inflammatory effect.
Side effects
During the studies, no serious side effects were recorded; on the contrary, the drug increased the body’s protective properties. GHRP-6 is prescribed even in childhood.
Storage condition:
- In powder at +2-8C - up to 2 years;
- In powder at room temperature - up to 30 days;
- In solution at +2-8C - up to 20 days;
- In solution at room temperature - up to 3 hours.
It must be stored in a dark place; freezing is not advisable.
Course of GHRP-6 + MGF Peg for weight
An excellent course that allows you to gain significant amounts of quality muscle mass.
Course content: GHRP-6 + MGF Peg
Duration: 2 months
Dosages and regimen:
We put GHRP-6 in the morning and evening at 200 mcg, MGF Peg in training days We put 200 mcg after training, on normal days in the middle of the day the same 200 mcg.
Course GHRP-6 + HGH Frag 176-191 for the drying period and to increase strength indicators
GHRP-6 for one injection 100 mcg (you need to do 3 per day), HGH Frag 176-191 for one injection 200 mcg (3 times a day along with GHRP-6). We give the first injection immediately after waking up GHRP-6 + HGH Frag 176-191. After 5 hours we again set GHRP-6 + HGH Frag 176-191. We give the last injection an hour and a half before bedtime GHRP-6 + HGH Frag 176-191.
Course GHRP-6 + GRF (1-29) for mass, strength and fat burning
The synergistic effect significantly increases the level of somatotropin release. The reason why GHRP-6 and GRF (1-29) should be taken together is that they are analogues of two completely different groups substances. GHRP-6 are analogs of OGF (opioid growth factor or Met-enkephalin), and GRF (1-29) are analogs of GHRH (growth hormone releasing hormone). Their mechanisms of action are different, but both cause the release of growth hormone, and if taken together, then the release of growth hormone will be stimulated “from different sides.” Please note - GHRP-6 and GRF (1-29) act on different receptors, so you don't have to worry about ineffectiveness and receptor overload.
Course duration:
2 months (weight 80-100kg)
Dosages and regimen (3 times a day):
- 100 µg GRF (1-29) along with 200 µg GHRP-6 in the morning 25 minutes before meals;
- 100mcg GRF (1-29) along with 200mcg GHRP-6 6 hours later, ideally immediately after training.
Peptides for mass, strength, weight loss, tanning - detailed instructions
What do you need to buy in addition to the peptides?
Buying peptides is not enough to start a course. After all, most peptide bioregulators are initially in dry form, and in order to bring them into a ready-made state, you must first dilute them and then inject them using an insulin syringe.Therefore, to start the course you will need to additionally buy: a special, for administering peptides internally, as well as(not necessary).Let's look at each element in more detail:
How to calculate the dosage of peptides on an insulin syringe?
It is important not only to know the correct dosage of peptides, but also to be able to calculate it. Almost 100% of the success of the course depends on this. After all, if you understand this point incorrectly, then if the amount of the active substance is insufficient, you will not get the desired result, and if it is too high, you increase the risk of side effects. TO How to correctly calculate the required dosage of peptides on an ins syringe? To do this you need to know the three most important things:
- How many mg of peptide are in the bottle?
- What is the scale of the syringe and how much liquid “fits” in it?
- The amount of liquid with which the peptide was diluted
If the second and third points are static and rarely change. Let us remember that bottles with peptides are almost always diluted with 2 ml, and insulin syringes are used with a scale from 10 to 100 and a volume of 1 ml. Then the third one is almost always different. Vials of peptides are available: 2 mg (often this packaging is used for CJC-1295, ipamorelin, PEG MGF), 5 mg (GHRP-2; GHRP-6; TB-500) and 10 mg (Melanotan 2). Other options come across quite rarely. It is very important to understand that diluting different peptides with the same amount of water and using the same insulin syringes, when drawing the same amount of solution, the dosage will change based on the initially stated mg in the vial: 2 mg or 5 mg or 10 mg. For example, 10 units of GHRP-6 5 mg will equal 0.25 mg (250 mcg), and 10 units of CJC-1295 2 mg = 100 mcg. Next, we will look at this moment in more detail, along with a photo.
Algorithm for calculating the dosage of peptides using a real example
Information in text form may be difficult for beginners to understand. Therefore, next we will look at a detailed analysis in pictures: how, what and why. So the most famous weight gain kit is GHRP-6 and CJC-1295. Before us are these peptides, as well as liquid for dilution, insulin and simple syringes. All is ready!
1. We dilute peptide bioregulators. Add 2 ml of liquid to each.
2. Peptides are diluted. Thus, it turned out that GHRP-6 5 mg is diluted with 2 ml and the releasing peptide CJC-1295 is also diluted with 2 ml. We remember the values, they will be useful to us in the future.
3. Used ins syringes with marks from 10 to 100 units. Where 100 is the maximum value equal to 1 ml. That is, we can say that the peptides are diluted with two full insulin syringes. By the way, 1 mg = 1,000 mcg.
4. Thus, we can say that GHRP-6 5 mg is diluted with 2 ml or 5 mg = 2 ml. This, if converted into other measurements, will be: 5,000 mcg = 200 units. Next, we calculate that 1 unit is equal to 25 mcg. Same with the CJC-1295. Bottle 2 mg = 2 ml or 1 unit equals 10 mcg.
10 units of CJC-1295 = 100 mcg of substance
Peptides GHRP-6 150 mcg and CJC-1295 - 100 mcg
Do not forget that usually one division on an insulin syringe = 2 units, which means 4 units = 2 divisions on an insulin syringe.
How to properly inject peptides?
It's no secret that most peptides come in the form of a solution, rather than capsules or tablets. Therefore, their use is carried out by injection. In one of our studies, we found that peptides are equally effective when administered subcutaneously and intramuscularly. There are practically few effects when administered nasally and useless when administered orally. Agree to use the peptide with a thin 5 mm needle, it is better to pierce yourself more than 5 cm each time. Therefore, 99% of users who use peptides do so subcutaneously using an insulin syringe. Now very important question where to inject peptides? We also carefully studied this issue. To do this, the athlete injected himself into the biceps area and passed a growth hormone test, which shows the work of the peptide. Then the same thing was done after injection into the fat fold - the result was almost identical. Therefore, the place of injection of peptides does not play a big role, but it is worth saying that the fat fold on the abdomen is the most convenient option.
Now let's look at another important question. How to properly inject peptides? Very often, when users hear that the injection is performed in the fat fold, they begin to say that they do not have it, since the percentage of fat is low. But it is not so. You should take the skin in your hand, then the fat fold will miraculously appear. Next, the entire length of the needle is inserted perpendicularly into it. Then you should slowly press the plunger of the insulin syringe. To make taking peptides as painless as possible, it is recommended to first warm the active substance in your hand for several minutes. You can see an illustration of all this above!
Peptide storage
Peptide bioregulators are quite specific agents. Their peculiarity is that in order to preserve their qualities, they must be kept in the cold. However, many resources clearly go too far with this, recommending the purchase of various cold elements or cold accumulators for almost every order, which will reach the client in no more than 10 days. Whatever the peptide is, in dry form, in the absence of sunlight falling on it, it will be stored for at least 60 days at temperatures up to 45 degrees. Hard to imagine? This is exactly the information we received from the manufacturer of one of the brands. In the refrigerator, the shelf life of peptides increases to 1-1.5 years. And in the freezer at minus 30 degrees there is so much that the manufacturers themselves do not know. It’s another matter when the peptide is already dissolved. In this form, he can stay for no more than 1 day. From 2 weeks to a month depending on the solvent. And it’s better not to freeze it. Although this one went well! In more detail, you can read about the shelf life of peptides in dry and liquid states.
How many days can you take peptides?
There are quite different opinions on this question. We believe that optimal duration The course is considered to be from 1 to 2 months. In exceptional cases - 3 months. The duration depends on many factors: what peptides are used, the goals of the course, dosage and the individual characteristics of the user. More accurate data in the table.
Many people still ask questions, and how long to rest after a course of peptides so that later you can start a new one? It should be understood that even the safest course of peptides, one way or another, puts some kind of stress on the body, forcing it to work harder. It can be compared to driving fast in a low gear at high revs.
Peptides GHRP-6 and CJC-1295
Therefore, for further progress you need to give enough time for rest. So the minimum interval between courses is no less than the duration of the course itself. Whereas we do not recommend doing more than 3-4 courses per year. After all, the body must be able to progress on its own, and not “get hooked” on external helpers. Then the peptides will always please you, and the progress will be constant.
Where to get peptides
Today, you can buy a course of peptides in a couple of mouse clicks. However, finding truly high-quality products is somewhat more difficult. Our online store offers you to purchase peptides from the manufacturer at best prices, the highest degree of purification with delivery throughout Russia! To select, it is recommended to visit our section, where best options with discounts and detailed instructions!
Results of a monthly course of peptides
To order, you need to add the product you are interested in to your cart and complete your purchase. Or you can do it even faster by writing to us
for 2 months Description GHRP 6 is an excellent drug from the group of GHRP peptides, thanks to which you can increase strength indicators or gain high-quality lean muscle mass. Ten bottles of GHRP 6, 5 mg each, are enough for one course, with a daily dosage of 600 mcg (3 injections of 200 mcg of active ingredient).
for 2 months
- Description
GHRP 6 is an excellent drug from the group of GHRP peptides, thanks to which you can increase strength indicators or gain high-quality lean muscle mass. Ten bottles of GHRP 6, 5 mg each, are enough for one course, with a daily dosage of 600 mcg (3 injections of 200 mcg of active ingredient). GHRP 6 needs to be administered as a subcutaneous injection into the fat layer, and the stomach is best suited for this. Injections should be given no earlier than an hour after meals, on an empty stomach, 3 times a day. After the injection, it is forbidden to eat fatty or carbohydrate foods, only protein foods are allowed, but preferably only 40 minutes after the last injection. The effect of the course will be enhanced by the additional use of L-arginine, L-glutamine and D-aspartic acid. Thanks to GHRP 6, you can get lean, gain quality muscles and increase your strength.
Two-month course of GHRP 6 peptides – how to dilute?
Before using the drug, you need to dilute it, following certain instructions. If you ignore them, then in the future the quality of the active substance may deteriorate significantly. To dilute the dry substance, you will need a regular two-piece syringe and sterile liquid for injection. Water for injection in the amount of 2 milliliters must be drawn into the syringe by opening the plastic cap. Next, the contents of the syringe are injected through a soft rubber plug, which must not be opened under any circumstances, otherwise the substance will lose sterility! You need to introduce water into the dry substance slowly and in a small stream so that it flows down the walls of the bottle. After administration, the resulting solution is stirred smoothly in a circular motion, no sudden shaking is allowed.
GHRP 2 or GHRP 6 – which is better?
These two peptide drugs belong to the same group of GHRPs and their principle of action is the same. The only significant difference is that GHRP 6 is a more advanced drug. Unlike GHRP 2, it does not so strongly imitate the production of the hormone ghrelin. Ghrelin is a hormone that increases appetite. Accordingly, using GHRP 6 you don’t have to worry about your appetite increasing too much. This drug is perfect for those who want to gain more strength without significantly gaining weight. GHRP 6 in this case is suitable for strength athletes who are limited by their weight category. If a training athlete has a goal not only to become stronger, but also to gain weight, then it is better to purchase GHRP 2.
Both drugs do not dramatically affect the hormonal levels of those taking the peptides. With long-term use of GHRP 6 or GHRP 2, prolactin and cortisol levels increase, especially if GHRP 2 is taken. If GHRP 6 is used, the increase in hormones is not as significant, but it is still there. To reduce the concentration of prolactin, you can take prolactin blockers like Dostinex during the course. To reduce cortisol, it is advisable to take more during the course whey protein, casein, drink essential amino acids branched chain amino acids (BCAA), vitamins and minerals. You cannot mix both peptides GHRP 6 and GHRP 2 in one course for supposed synergism; this is a dangerous misconception among many novice athletes. Since the nature of both drugs is the same, they begin to act on the pituitary gland with a double effect, overloading it, resulting in harm to the body, and the drugs are normally perceived, since sensitivity receptors stop responding to such dosages and a large amount of unwanted hormones cortisol and prolactin are produced .
For the course GHRP-6 you will need
GHRP-6 (5 mg) – 10 bottles
A course of GHRP-6 for one month is also available for sale.
We have already received a lot of feedback on the use of the GHRP-6 peptide course. The reviews are extremely positive. The course is successfully taken by athletes to increase muscle mass and strength. We invite you to read the existing reviews, and we will also be grateful if you share your opinion about the drug after using it.
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Customers who bought GHRP-6 Peptide Course (2 months) also bought
Source: peptid-premium.ru
Ghrp-6 course
GHRP-6 course used for the purpose of gaining muscle mass and improving its quality, although the drug is not used for “cutting”, since it significantly increases appetite. The GHRP-6 course, in general, receives very negative reviews, since athletes either do not feel any results or the result does not satisfy them. The drug is often counterfeited by mixing steroids into it, so there were even precedents for failing doping control. The only effect that occurs more or less regularly is an increase in strength, but it is accompanied, just as regularly, by an increase in fat. In general, most likely, an increase in strength indicators while gaining total body weight is the result that real GHRP-6 can give by increasing appetite.
The bottom line is that GHRP-6 is a derivative of ghrelin peptide, which is responsible for human appetite. The course of GHRP-6 simply stimulates the secretion of ghrelin, as a result of which appetite increases, a person eats more, and, accordingly, recovers faster, gains overall weight and becomes stronger. It seems to be good for peptides, but gaining such raw muscle mass involves the further utilization of subcutaneous fat, which will inevitably lead to a loss of muscle mass and strength indicators. The result is a vicious circle, the efficiency of which tends to zero. Professionals do not use peptides, preferring a growth hormone, but if they worked, the pros would use them!
Yes, peptide dealers, led by the main “everything for the boys of all Rus',” shout with one voice that peptides are much cheaper, therefore, if you compare the financial costs of a course of peptides and growth hormone of equal effectiveness, then peptides will cost less. The problem is that growth hormone actually works, but peptides most likely do not. In any case, their contribution will be very insignificant, since growth hormone is rarely given alone, but in a compote with pharma It is probably unrealistic to determine the effectiveness of peptides. In a word, we do not recommend that you buy peptides, but if you still want to try them or have already purchased GHRP-6, but do not know how to use it, then the following information will be useful to you.
GHRP-6 course: practice
Preparation: the solution is prepared using bacteriostatic water or water for injection, which requires 1 or 2 ml; it should be poured into the bottle along the wall, then the bottle is not shaken, but the solvent and the peptide are mixed in a circular motion.
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Course duration: 4-8 weeks, since at 8-12 weeks tolerance to the peptide develops, as a result of which its use loses all meaning; the break between courses should be 1-2 weeks.
Method of administration: You can even take the drug orally, but the optimal method of administration is injections, which can be done intramuscularly or subcutaneously, but it is better to do it intramuscularly, since it is possible that a steroid has been added to the peptide, so to avoid unpleasant consequences, put it in the ass. Important* syringe for intramuscular injections!
Sports pharmacology
Attention, TODAY only! Similar
Source: sport4wiki.ru
Peptides are drugs that stimulate the production of androgenic growth hormone. They are produced by different manufacturers, and among the most popular is GHRP-6. The drug is advertised not only as a peptide that improves the quality of recovery processes after hard training, but also as a means taken for faster rehabilitation after suffering an injury.
Action of the peptide
GHRP-6 injections have a wide range of actions that are still being researched. Taking the peptide is generally believed to lead to the following changes:
- Increases the concentration of androgenic growth hormone in the body with all its inherent consequences. The use of the product, as users note, normalizes sleep, helps to recover faster after training, and also reduces body fat without a strict diet and does not feel overtrained.
- Speeds up metabolism and increases appetite. There is no effect of suppressing hunger, but, on the contrary, an incentive to consume more food in relation to growth hormone allows you to gain lean muscle mass.
- Rejuvenates the body. The effect is manifested not only in internal changes, but also in external ones, when the skin is tightened and smoothed.
- Has a beneficial effect on the circulatory system. Blood sugar levels also decrease, and the concentration of bad cholesterol decreases significantly.
- Increases resistance to infections. The body's protective and anti-inflammatory response is enhanced.
- Indicators of muscle endurance increase. This has a positive effect on the training process.
The peptide has effects that allow the drug to be used by those involved in bodybuilding, but it is of little use for weightlifters and powerlifters, since it has virtually no effect on strength indicators.
And if most peptides are used for weight loss, then GHRP-6 is not suitable for these purposes without taking other drugs, as it helps increase appetite. The product should be taken by those who not only want to lose weight, but also gain lean muscle mass.
How to take GHRP-6
The dosage of the drug is determined by the degree of digestibility. For every kilogram, about 100 mcg of peptide is usually taken. If the dosage is increased, the secretion of growth hormone will increase by no more than 20 percent, so it is best to stick to the optimal rate.
Injections are performed three times a day. They are done a quarter of an hour before meals, as well as before training. The level of growth hormone begins to rise after half an hour, and drops to the previous norm within 2 hours.
The GHRP-6 peptide course also includes GHRP-2. Their combined use has a synergistic effect. The total duration of the course is determined individually, but varies between 6-12 weeks.
Side effects
The only disadvantage of taking this peptide is the increase in appetite. This may cause certain problems in the first two or three weeks after starting the course, but, as those taking the drug note, it goes away later. Itching may occur at the injection site, which often happens when taking peptides.
The drug is usually written about by those who refuse growth hormone because of the high cost, noting that the drug is close in its effect to solo GH, but without the need to additionally administer thyroid hormones. There are also openly negative reviews.
In reality, as those dissatisfied with the peptide write, there is practically no result, and if we compare the products with pharmacological drugs, then it does not work. There are those who are dissatisfied with the need to consume large amounts of sports nutrition. There are reviews with test results that confirm the real increase in growth hormone.
Source: builderbody.ru
GHRP 6 peptide is one of the most popular growth hormone stimulants. This is due to the fact that for its price the drug demonstrates an excellent effect, is safe for health and is suitable not only for professional athletes, but also for amateurs. The market is represented by several manufacturing companies, mainly Chinese.
GHRP 6 is a substance that stimulates the secretion of growth hormone in the human body. The drug was invented to eliminate somatotropin deficiency in children and adults. There is a similar medication called Hexarelin. It has the same dosages, properties and disadvantages. Some sources consider these two drugs as one because of their identity. The same cannot be said about GHRP 2. The key difference between this peptide and GHRP 6 is the strength of action (GHRP 2 is almost 2 times more powerful), but along with the effect, side effects also increase (increased levels of prolactin and cortisol). They are often combined to achieve synergy. We will talk about this combination later, but for now let’s turn our attention to the principle of action and effectiveness of GHRP 6.
Numerous studies of the drug are still being conducted. New ones open up every time beneficial features GHRP possesses. To the main positive effects Its uses include the following:
- Increased somatotropin levels;
- Increase in muscle mass;
- Increased endurance;
- Acceleration of recovery processes and wound healing;
- No overtraining;
- High-quality fat burning due to the fat layer, not muscle fibers;
- Deep sleep;
- Strengthening the osseous-ligamentous apparatus;
- Acceleration of metabolism;
- Immune system support;
- General rejuvenating effect on the condition of the skin, nails and hair;
- Lowering blood sugar and cholesterol levels;
- Protection of liver function.
Since the drug does not have a strong effect on strength indicators, it has not found wide use in powerlifting and weightlifting. The effect of the GHRP 6 course is most valued in bodybuilding.
Unlike many analogues, the substance is rarely used as a means of weight loss due to its appetite-enhancing properties. It is more advisable to use GHRP 6 while working to build high-quality muscle mass.
The absence of side effects is one of the key advantages of the drug. No serious side effects were identified either during clinical studies or during widespread use, as evidenced by positive reviews on the Internet.
People who used GHRP 6 noted only a significant increase in appetite in the first 2 weeks after starting the course and a slight burning sensation on the skin at the injection sites (a normal reaction of the body to frequent injections).
At very high dosages (from 650 mcg per day), high levels of cortisol and prolactin were observed. But if you follow the recommendations and adhere to standard dosages, the risk of this side effect will be minimal.
The question of how to take GHRP 6 still remains relevant. The fact is that the molecules of the active substance are tiny in size, which allows them to pass through the vessels of the oral cavity and gastrointestinal tract before digestive enzymes have time to destroy them. Therefore, the drug can be found not only in the form of injections, but also in tablet form. However, studies have found that injections guarantee better effectiveness and faster transport of the substance. Injections are best given intramuscularly.
The standard dosage is 100 mcg three times a day 20-30 minutes before meals. This amount of the drug, half an hour after administration, will increase the secretion of growth hormone by more than 20% and within 3 hours the level of somatotropin will smoothly return to natural.
After 2-3 months of use, the body begins to adapt to the substance and react to it to a lesser extent. Therefore, it is advised not to extend the course for more than 2-2.5 months, and be sure to take a break of 2 to 3 weeks.
Cooking process:
Preparation of a solution with GHRP 6 is no different from analogues.
- Bring the substance to room temperature.
- Inject injection water along the wall of the bottle with an insulin syringe.
- Stir gently in a circular motion until completely dissolved.
The prepared solution of GHRP 6, unlike other peptides, is characterized by a long shelf life. It can be stored in the refrigerator for about a month. After which it will lose all its beneficial properties.
Important! In this case, it does not matter whether bacteriostatic or injection water was used.
Despite the fact that GHRP 6 performs well in a solo cycle, it is most often used in combination with other peptides or anabolic steroids. Let's look at the most popular and effective options:
- GHRP 2 and GHRP As already noted, the combination interacts well and complements each other.
- GHRP 6 and GRF 1-29. This combination of drugs is considered the best among peptide substances. The tandem of these drugs not only enhances the course by more than 3 times, but also solves the issue of desensitization (accustoming the body to the drug).
- GHRP 6 and HGH Fragment 176-19. Used to increase strength and maintain muscle mass during a diet.
- GHRP 6 and insulin. Insulin has positive influence on the course results, increasing them by about 35-40%.
- GHRP 6 and sports supplements. It would not be amiss to use amino acids such as arginine, glutamine and GABA during the course. They can enhance the effect of the course by 15-25%.
GHRP 6 is an excellent means of stimulating growth hormone, demonstrating a satisfactory effect for its cost. This is evidenced by the loyal attitude of customers towards the product and positive reviews on the Internet. You can also buy other peptides in Moscow from us.
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GHRP-6 and Hexarelin (from the English Growth Hormone Releasing Peptide - 2 - peptide that releases growth hormone and from the English Hexarelin) are stimulants of growth hormone secretion. Hexarelin is a structural analogue of GHRP-6, has the same effects, is used in the same dosages, so they are often considered synonyms.
These substances were developed to treat growth hormone deficiency.
GHRP-6 is in many ways similar to GHRP-2, the main difference is that the second is approximately 1.5 times more powerful growth hormone booster, can increase appetite somewhat more strongly (although comparative studies have not been conducted), but at the same time increases the concentration of prolactin and cortisol.
These peptides can be used together to achieve a synergistic effect.
In studies, the maximum concentrations of growth hormone in the blood were observed with the combined administration of GHRP-6 and GHRP-2.
Recently, erroneous opinions have been spreading about the effect of these ghrelin agonists on appetite, especially when doctors from the Iron World published an article (Peptides part 1, author Dmitry Ustimenko), where they wrote: Ghrelin is an appetite hormone.
Stimulated by GHRP-6 and GHRP-2.
Ghrelin release is influenced more by GHRP-6 than by GHRP-2.
This is a gross misconception, since they in no way stimulate the production of ghrelin, but are mimetics to its receptors.
At the same time, GHRP-2 has greater affinity, and in addition, the effect of cortisol is additionally superimposed, which also increases appetite.
As a result, illiterate readers of the magazine, deprived of the ability to critically think, began to actively replicate false information.
The article contains many other errors and false statements regarding effects and pharmacodynamics.
Hexarelin and GHRP-6 can be administered into the body in various ways: subcutaneously, orally, sublingually, buccally, but most often intramuscularly.
The molecules of this substance are so small that they are able to penetrate the blood vessels of the mouth and stomach before being destroyed by digestive enzymes.
Application in bodybuilding
Despite the fact that this is a new drug, Hexarelin has already become a popular choice for athletes as a means to increase endurance and increase muscle definition. GHRP-6 is available in several brands.
Action
The main effect of GHRP-6 is to stimulate the secretion of growth hormone, so most of the effects are similar to those of growth hormone.
The main effects of GHRP-6 are listed below:
- Increase in strength indicators
- Muscle growth;
- Fat burning;
- Increased relief;
- Increased appetite;
- Strengthening immunity;
- Strengthening bones;
- Protects the liver;
Research data
In studies when Hexarelin was administered subcutaneously, growth hormone concentrations increased significantly within thirty minutes after administration.
Over the next four hours after the injection, the concentration of growth hormone gradually decreases to the initial level.
Doses and regimen
Tests have shown that the optimal single dose of GHRP-6 is 1 mcg per 1 kg of body weight. When the dose is reduced, a weaker rise in growth hormone is observed, but exceeding the specified dose does not lead to an increase in the secretion of growth hormone.
For example, when increasing the dose from 100 to 200 mcg, the increase in growth hormone concentration will differ by only 25%, so 100 mcg is considered the optimal dose for bodybuilding.
The drug is administered three times a day - after training, 15 minutes before meals and before bedtime.
It was also determined that the body gradually adapts to the action of GHRP-6, and the effectiveness of the drug decreases accordingly.
In the people studied, tolerance (desensitization) occurred after 4-16 weeks of use.
For this reason, if you do not want to waste your financial resources, the duration of the course should not exceed 4-8 weeks, after which you need to take a break for 1-2 weeks.
The problem of desensitisation is also solved by the combination with CJC-1295; currently this “combination is recognized as the gold standard.”
Combination
The effectiveness of a GHRP-6 cycle can be significantly increased if you combine it with other growth hormone stimulants.
- CJC-1295 or GRF(1-29) is the best choice for combination. They enhance the effect of GHRP-6 several times. This combination is currently recognized as the gold standard in bodybuilding. Combined courses are described in the links provided.
- GHRP-2 - will increase the effectiveness of the course by more than 2 times
- Insulin - will increase the effectiveness of the course by 30-40%
- Arginine - will increase efficiency by 10-20%
- Glutamine
- GABA
Side effects
During the studies, no serious side effects of GHRP-6 were recorded; on the contrary, the drug increased the body’s protective properties. GHRP-6 is prescribed even in childhood. At higher doses (600 mcg/day and above), it can cause an increase in the concentration of prolactin and cortisol, but to a much lesser extent than GHRP-2. A burning sensation occurs at the injection sites, which goes away after 5-10 minutes.
GHRP-6 course for strength and muscle mass
Here you will need to give 3 injections per day of 100 micrograms of the substance.
Inexpensive and effective course for 2 months.
GHRP-6 should be administered no earlier than 40-60 minutes after a meal; after GHRP-6, do not eat carbohydrates and fats; ideally, it is better not to eat anything.
After 40 minutes, the release of growth hormone begins to decline and then you can eat.
Proteins prolong the release, especially glutamine, arginine, D-aspartic acid.
Result:
- Muscle growth;
- Fat burning;
- Increased relief;
- Anti-aging effect (improving the properties of skin and hair);
- Strengthening immunity;
- Strengthening bones;
- Protects the liver;
- Anti-inflammatory effect.
Basic combined course CJC-1295 + GHRP-6
It has been well proven and well established that the simultaneous administration of GHRH (eg, CJC-1295) and GHRP (eg, GHRP-6 or GHRP-2) leads to a synergistic effect.
These peptides have a potentiating effect on each other.
In other words, with the introduction of one CJC-1295 we will get a stimulating effect of 2 points.
When introducing GHRP-6 alone, we get an effect of 4 points.
When both substances are administered simultaneously, we will get an effect not of 6 points (additive effect 2+4=6), as one might expect, but of 10 points - more than the sum of each separately (potentiating effect 2+4=10).
This way we not only get a greater anabolic response, but we can also save money.
While CJC-1295 maintains the natural GH surge, it does not cause an increase in these peaks, only increasing basal GH levels, thereby creating a female-type concentration pattern with less anabolic response.
Moreover, GHRH are only effective when somatostatin levels are low.
Therefore, combining CJC-1295 and GHRP-6 or GHRP-2 allows you to maintain the natural curve, and adjust the time and height of concentration peaks.
Optimal combined course:
- GHRP-6 or GHRP-2 100 mcg three times a day.
- CJC-1295 1000 mcg twice a week.
- Course duration is 8-12 weeks.
CJC-1295 course without DAC
Optimal dose of CJC-1295 without DAC: 1 mcg/kg up to three times daily (by subcutaneous injection) (2 mg ampoule = 2000 mcg). Thus, with a weight of 90 kg, the relevant dosage would be 90 mcg, and one bottle will last for 8-22 days (depending on the frequency of use).
It is also advisable to combine this peptide with GHRP-6 or GHRP-2. For example, the standard protocol looks like this: one injection contains 100 μg of GHRP-6 + 100 μg of modified GRF (1-29).
Can be dissolved in one syringe.
The solution is diluted 2-3 times a day, with a difference of at least 3 hours. The best time for injections: after training, 15 minutes before meals and before bed!
- 100mcg CJC-1295 along with 200mcg GHRP-6 in the morning 25 minutes before meals
- 100mcg CJC-1295 along with 200mcg GHRP-6 6 hours later, ideally immediately after training
- 100mcg CJC-1295 along with 200mcg GHRP-6 immediately before bed
Main effects:
- Increase in strength indicators;
- Muscle growth;
- Fat burning.
Minor effects:
- Strengthening immunity;
- Rejuvenating effect;
- Increased relief;
- Protects the liver;
- Anti-inflammatory effect.
Side effects
Storage condition:
Course of GHRP-6 + MGF Peg for weight
An excellent course that allows you to gain significant amounts of high-quality muscle mass.
Course composition: GHRP-6 + MGF Peg
Duration: 2 months
Doses and regimen:
We put GHRP-6 in the morning and evening at 200 mcg, on training days we put MGF Peg after training at 200 mcg, on normal days in the middle of the day we also put 200 mcg.
Course GHRP-6 + HGH Frag 176-191 for the drying period and to increase strength indicators
GHRP-6 for one injection 100 mcg (you need to do 3 per day), HGH Frag 176-191 for one injection 200 mcg (3 times a day along with GHRP-6). We give the first injection immediately after waking up GHRP-6 + HGH Frag 176-191. After 5 hours we again set GHRP-6 + HGH Frag 176-191. We give the last injection an hour and a half before bedtime GHRP-6 + HGH Frag 176-191.
Course GHRP-6 + GRF (1-29) for mass, strength and fat burning
The synergistic effect significantly increases the level of somatotropin release. The reason why GHRP-6 and GRF (1-29) need to be taken together is that they are analogues of two completely different groups of substances. GHRP-6 are analogs of OGF (opioid growth factor or Met-enkephalin), and GRF (1-29) are analogs of GHRH (growth hormone releasing hormone). Their mechanisms of action are different, but both cause the release of growth hormone, and if taken together, then the release of growth hormone will be stimulated “from different sides.” Please note - GHRP-6 and GRF (1-29) act on different receptors, so you don't have to worry about ineffectiveness and receptor overload.
Course duration:
2 months (weight 80-100kg)
Doses and regimen (3 times a day):
- 100 µg GRF (1-29) along with 200 µg GHRP-6 in the morning 25 minutes before meals;
- 100mcg GRF (1-29) along with 200mcg GHRP-6 6 hours later, ideally immediately after training;
- 100mcg GRF (1-29) along with 200mcg GHRP-6 just before bed.
Main effects:
- Increase in strength indicators;
- Muscle growth;
- Fat burning.
Minor effects:
- Strengthening ligaments, joints, bones;
- Strengthening immunity;
- Rejuvenating effect;
- Improving the properties of skin and hair;
- Increased relief;
- Protects the liver;
- Anti-inflammatory effect.
Its effectiveness is equal to a growth hormone cycle of 15 units/day, while the cost is several times lower.
Side effects:
During the studies, no serious side effects were recorded; on the contrary, the drug increased the body’s protective properties. GHRP-6 is prescribed even in childhood.
Storage condition:
- In powder at +2-8C - up to 2 years
- In powder at room temperature - up to 30 days
- In solution at +2-8C - up to 20 days
- In solution at room temperature - up to 3 hours
It must be stored in a dark place; freezing is not advisable.
GHRP-6 is a peptide that stimulates the production of endogenous growth hormone. The effect is of medium strength; after the injection, a strong feeling of hunger is felt due to the effect on the hunger center in the brain.
Information
- Manufacturer: bluepeptides.com;
- Degree of purification: >98%;
- Amino acid sequence: His-D-Trp-Ala-Trp-D-Phe-Lys-NH2;
- Formula: C46H56N12O6;
- Molecular weight: 873,01;
- Approximate half-life: 2 – 2.5 hours;
- Warning: Is not medicine or a pharmaceutical substance. For research purposes only;
- Storage conditions: the drug should be stored in refrigerators at temperatures from 2 to 8°;
- Quality checking: At the bottom of this topic is a chromatography analysis.
- Wholesale: you can purchase these peptides in bulk; to do this, send your request to our email and we will send you a wholesale price list and terms of cooperation by return letter.
Description
GHRP-6 is a peptide that stimulates the body's production of its own growth hormone. Its action is similar to GHRP-2, the only difference is that GHRP-2 is more powerful (about 30%), but GHRP-6 increases the concentration of prolactin and cortisol less. And also another important difference between GHRP-6 and its “neighbors” is the occurrence of a very strong feeling of hunger (GHRP-6 acts similarly to the hormone ghrelin). These peptides can be used together, the resulting effect will be greater than the sum of the effects of GHRP-2 + GHRP-6, this is called a synergistic effect.
- Prolactin is a peptide hormone that stimulates the development of mammary glands (gyno);
- Cortisol is the main hormone that breaks down proteins, promotes the accumulation of fat in the body and increases blood glucose levels;
- Ghrelin is a hunger hormone that causes a person to feel hungry.
Main functions
The action of GHRP-6 is similar to GHRP-2 and its functions are explained essentially by the functions of growth hormone.
- increase in strength indicators;
- muscle growth;
- increased appetite;
- fat burning;
- improvement of muscle definition;
- increased appetite;
- strengthening immunity;
- rejuvenating effect (improving the properties of skin and hair);
- strengthening bones;
- liver protection;
- anti-inflammatory actions.
Application and dosage
- used in a dosage of 1-2 mcg per 1 kg of body weight, 2-3 times a day. (on average 100-200 mcg 3 times a day);
- injection of the drug should be carried out on an empty stomach - at least 2 hours after the previous meal and no less than an hour before the next one. It is advisable that the food taken before the injection contains some fat and carbohydrates;
- for prevention age-related changes(40+) one injection once a day is enough;
- on average, a solo GHRP-6 course lasts 1-2 months, followed by 1-2 weeks of rest to prevent excessive depletion of the pituitary gland;
- It is advisable to combine this drug with GHRP-2, CJC-1295, CJC-1295(DAC), Ipamorelin, since the effect of such a combination will not just double, but triple the result (synergistic effect).
Various combinations
To achieve better efficiency and benefits from taking GHRP-6, it is recommended to combine it with other growth hormone stimulants or anabolic steroids.
- CJC 1295 + GHRP-6 or CRF(1-29)+ GHRP-2 is an excellent combination. The use of these peptides together enhances the effect of both several times. This combination has proven itself well and is firmly established in practical application many athletes;
- GHRP-2 + GHRP-6 together achieve a synergistic effect;
- Insulin + GHRP-6 - increases the effectiveness of the course by 30-40%;
- Arginine + GHRP-6 – increases the effectiveness of use by 10-20%;
- Glutamine + GHRP-6;
- GABA + GHRP-6.
Preparation of solution for injection
You should cool the bottle to room temperature, then add the required volume of water for injection (which should flow down the wall of the bottle) and stir with smooth rotating movements (do not shake) or let it stand in the refrigerator. The solution is quite stable. Moreover, stability in this case does not depend on the type of solvent (bacteriostatic water or water for injection).
- GHRP-6 (5 mg = 5000 mcg);
- We use 1 ml syringes with exactly 100 divisions, in which one division is 0.01 ml.
Use sterile water for injection, add 3 ml of water to the vial with GHRP-6, before wiping the rubber cap on the vial with alcohol. For a 100-bar insulin syringe, one bar will yield 16 mcg of GHRP-6. Or add 2 ml of water for injection, then 1 division (1 unit) = 25 mg. It is very important to maintain sterility during injections and while preparing the solution, because if bacteria enter, they will simply eat the peptide.
- use an insulin syringe with 100 insulin units U100;
- do not confuse insulin units with divisions;
- strictly follow the dosage and recommendations of this article;
- increase the amount of proteins in daily diet up to 3 grams per 1 kg of weight;
- keep an injection diary so you don’t forget what to inject and when;
- give injections in the same sequence. (so as not to confuse the drugs and not inject the same thing twice);
- in the abdominal area there are places where the injection is painless and vice versa;
- try to avoid injections into blood vessels;
- After the injection, do not pull out the syringe for 5-10 seconds to prevent the drug from leaking out;
- carry out the injection with clean hands;
- wipe the neck of the peptide ampoule with alcohol before use;
- wipe the injection site with alcohol (can be neglected, since the risk of infection is too small if you use insulin syringes);
- prevent the needle from touching non-sterile surfaces;
- prevent air from entering the syringe;
- the syringe is used only 1 time (to save money, you can take the daily dose of 1 drug into a separate syringe).
How is the injection done?
- The recommended injection site is the abdominal area 8 cm from the navel;
- give the injection strictly on an empty stomach;
- do not eat for 40-60 minutes after the injection;
- the break between injections should be at least 4 hours;
- wash your hands with soap;
- draw the drug into an insulin syringe;
- With your left hand, gather the skin into a fold on your stomach;
- insert the needle at an angle of 45° parallel to the fold;
- inject the drug and remove the needle;
- do not inject in the same place.
It is not necessary to treat the injection site when using insulin syringes; these are the recommendations of doctors. The puncture is not too big for infection to occur, but of course it’s better to be on the safe side.
Storage
- dry powder is recommended to be stored in normal refrigeration chamber at a temperature of about 2-8°C – (the shelf life in this case is up to 1 year, or after the expiration date indicated on the bottle);
- at a temperature of minus 18-20°C, the powder can be stored for up to several years;
- light can destroy powder, as well as oxygen, although peptides are not affected to the same extent by the latter. In any case, the seal of the package should not be violated - air trapped inside will slowly lead to the destruction of the peptide;
- the resulting solution cannot be frozen, and its shelf life is 30-35 days in the refrigerator;
- The solution is best stored at a temperature of 2-4°C, the permissible level is up to 8°C.
Side effects
During the studies, no serious side effects of GHRP-6 were recorded; on the contrary, the drug increased the body’s protective properties. GHRP-6 is prescribed even in childhood. At higher doses (600 mcg/day and above), it can cause an increase in the concentration of prolactin and cortisol, but to a much lesser extent than GHRP-2. A burning sensation occurs at the injection sites, which goes away after 5-10 minutes. Prolactin levels can be reduced with a drug such as Dostinex.
Results of chromatography analysis (product quality check):
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